Preclinical study index · Research use only

Thymosin Alpha-1: preclinical and in-vitro studies

8 published studies on Thymosin Alpha-1, limited by rule to animal models and cell-based (in vitro) work indexed in PubMed, spanning 2015 to 2024 across 8 journals. Human trials, case reports and literature overviews are excluded. Titles appear as published; each links to its PubMed record and, where one is registered, its DOI.

  • 8studies listed
  • 8with an animal model
  • 3with in-vitro work
  • 2015 to 2024publication years
  • 8journals

Evidence table

#YearStudyJournalModelRecord
1 2024 Thymosin α1 reverses oncolytic adenovirus-induced M2 polarization of macrophages to improve antitumor immunity and therapeutic efficacyPMID 39357524 Cell reports. Medicine Mice model and in vitro PubMed · DOI
2 2023 Immunological effects of heated intraperitoneal chemotherapy can be augmented by thymosin α1PMID 36758296 International immunopharmacology Mice model PubMed · DOI
3 2020 Thymosin α1 protects from CTLA-4 intestinal immunopathologyPMID 32817121 Life science alliance Mice model PubMed · DOI
4 2020 Immunopotentiator thymosin alpha-1 attenuates inflammatory pain by modulating the Wnt3a/β-catenin pathway in spinal cordPMID 31764244 Neuroreport Mice model PubMed · DOI
5 2018 Effect of a C-end rule modification on antitumor activity of thymosin α1PMID 30096371 Biochimie Mice model and in vitro PubMed · DOI
6 2018 Gene cloning, expression and immune adjuvant properties of the recombinant fusion peptide Tα1-BLP on avian influenza inactivate virus vaccinePMID 29730515 Microbial pathogenesis Mice and Chick embryo model PubMed · DOI
7 2015 Thymosin α1 promotes the activation of myeloid-derived suppressor cells in a Lewis lung cancer model by upregulating Arginase 1PMID 26111447 Biochemical and biophysical research communications Mice model PubMed · DOI
8 2015 Thymosin alpha1 enhanced cytotoxicity of iNKT cells against colon cancer via upregulating CD1d expressionPMID 25304368 Cancer letters Mice model and in vitro PubMed · DOI

Studies by model

  • Mice · 8 studies
  • In vitro · 3 studies
  • Chick embryo · 1 study
  • Chickens · 1 study

What this index does not include

Human research of any kind: publications typed by PubMed as human studies or case reports, and papers whose titles or abstracts describe human subjects, are removed by rule. Literature overviews, meta-analyses, editorials and letters are removed because they summarise rather than report. Papers whose titles contain usage or outcome language that would not pass this site's research-use-only copy rules are dropped rather than reworded, since a published title is a fact that cannot be edited.

Nothing on this page is a statement about effects in humans, a recommendation, or a description of the material supplied. Thymosin Alpha-1 is supplied for laboratory research only.

How this index is built

PubMed is searched on the names the literature uses for Thymosin Alpha-1 (thymosin alpha 1, thymosin alpha-1, thymalfasin, Tα1), restricted to records indexed to an animal or cell model, in English, with an abstract. Clinical publication types, human-subject language and overview-type publications are excluded. The compound must be named in the title. Candidates are ranked by title match, indexing quality and year; the shortlist is read by a person before it is published, and a small blocklist holds records rejected on that read. The list was resolved on 2026-10-12 and is re-run deliberately, never on a timer.

Questions

Are there human studies of Thymosin Alpha-1 in this index?

No, by design. This index lists animal and cell-based research only. Publications typed as human studies, case reports or literature overviews, and papers whose titles or abstracts describe human subjects, are excluded by rule before anything is listed. Eon Peptides supplies Thymosin Alpha-1 for laboratory research and makes no statement about use in humans.

Which research models appear most often for Thymosin Alpha-1?

Across the 8 studies listed: Mice (8), In vitro (3), Chick embryo (1), Chickens (1). A model label is taken from PubMed's indexing of each paper, or from its title and abstract when the record is too new to be indexed. It describes the study, not the material.

How are the studies selected?

A PubMed search on the published names of the compound (thymosin alpha 1, thymosin alpha-1, thymalfasin, Tα1) is filtered to records indexed to an animal or cell model, with clinical publication types, human-subject language and overview-type publications removed. The compound must be named in the title. Remaining records are ranked by title match, indexing quality and year, and the top 8 are listed after a manual read. The list was resolved against PubMed on 2026-10-12.

Does a listing here say anything about the Thymosin Alpha-1 Eon Peptides sells?

No. A listing records that a study was published and what it examined. It says nothing about the properties, quality or intended use of any material. What Eon Peptides does document about its own Thymosin Alpha-1 is on the certificate pages: lot-level identity and purity results from independent laboratories.

Related pages

For research use only. Not for human or veterinary use. Preclinical and in-vitro studies only: animal models and cell-based work indexed in PubMed. Human trials, case reports and literature overviews are excluded by rule.