Melanocortin Signalling
PT-141 is characterised for MC3R and MC4R activity in central nervous system models.

Melanocortin + neurohypophysial peptide · 20 mg lyophilized
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Researchers also added
Research use only.
This is a blend. PT-141 and Oxytocin are combined in a single 20 mg vial, 10 mg of each. Both act on central nervous system signalling but at unrelated receptors: PT-141, also called bremelanotide, is a ring-shaped seven amino acid peptide that binds the melanocortin receptors MC3R and MC4R, while Oxytocin is a nine amino acid neurohypophysial hormone with an internal disulfide bridge that binds its own receptor, OXTR. The combination has not been characterised as a single formulation.
Cyclic heptapeptide MC3R/MC4R agonist + nonapeptide neurohormone (10 mg each)
The numbers that define PT-141 / Oxytocin and how it is being studied. For laboratory research use only.
PT-141 · Oxytocin
10 mg of each component
Melanocortin receptors
The pathways PT-141 / Oxytocin acts on - and what each one does. The animation traces its signal outward from the compound to every target it engages.
PT-141 is a cyclic heptapeptide that binds MC3R and MC4R. Research has measured its activity in the central nervous system rather than in blood vessels, which separates it from other compounds studied in the same area. Its structure derives from Melanotan II.
Oxytocin is a nine amino acid neurohypophysial hormone closed by a disulfide bridge between residues 1 and 6. It binds the oxytocin receptor OXTR, and social and affiliative behaviour endpoints have been measured in animal models.
The vial pairs a melanocortin agonist with a neurohypophysial hormone. The receptors are unrelated, the two are characterised separately, and no interaction data exists for the pair.
The main areas PT-141 / Oxytocin is being studied for - and the study-reported figures behind them.
PT-141 is characterised for MC3R and MC4R activity in central nervous system models.
Oxytocin is a long-established reference ligand for the OXTR receptor.
Both peptides are used as receptor-defined tools in binding and signalling assays.
One vial holds both peptides under matched handling.
An interactive 3D model rendered from the compound record - rotate and explore its structure.
Molecular model
| Components | PT-141 + Oxytocin |
| Content | 20 mg per vial (10 mg of each component) |
| PT-141 | Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-OH (bremelanotide) |
| Oxytocin | Cys-Tyr-Ile-Gln-Asn-Cys-Pro-Leu-Gly-NH₂, CAS 50-56-6 |
| Form | Lyophilized powder blend |
| Purity | ≥99% by HPLC |
| Appearance | White to off-white powder |
| Solubility | Water-soluble |
| Storage | -20°C, protected from light |
| Classification | Research use only |
Both are central nervous system signalling peptides studied in neuroendocrine research, though at unrelated receptors: PT-141 at MC3R and MC4R, Oxytocin at OXTR. One vial holds both under matched handling.
No. The melanocortin receptors and the oxytocin receptor are distinct receptor systems, and no interaction between the two has been characterised.
No. Each peptide is characterised separately and no interaction data exists for the pair.
The standalone PT-141 product lets you control its quantity independently and is offered in its own size. This vial fixes the ratio at 10 mg and 10 mg and adds Oxytocin.
Each lot is analysed by reverse-phase HPLC and released at ≥99%, with a Certificate of Analysis.
Store lyophilized at -20°C for long-term stability, protected from light and moisture, and avoid repeated freeze-thaw cycles.
Not for human or veterinary use. For in-vitro laboratory research only. These statements have not been evaluated by the FDA; this product is not intended to diagnose, treat, cure, or prevent any disease. Sold exclusively to qualified researchers and institutions.