This is a blend. MOTS-c and NAD+ are combined in a single 110 mg vial, 10 mg and 100 mg respectively. The two are not the same class of molecule: MOTS-c is a 16 amino acid peptide encoded in the mitochondrial genome and studied for AMPK signalling, while NAD+ is a coenzyme that carries electrons between reactions and is studied in mitochondrial metabolism, cell signalling and DNA repair. The combination has not been characterised as a single formulation.
The numbers that define MOTS-c / NAD+ and how it is being studied. For laboratory research use only.
2
Research Compounds
MOTS-c · NAD+
110 mg
Total Per Vial
10 mg MOTS-c + 100 mg NAD+
AMPK
MOTS-c Pathway
Metabolic regulator
4
Research Areas
Mitochondrial function
Metabolic regulation
DNA repair
How It Works
How MOTS-c / NAD+ works
The pathways MOTS-c / NAD+ acts on - and what each one does. The animation traces its signal outward from the compound to every target it engages.
Signalling pathways studied in preclinical models · illustrative
AMPK Signalling
MOTS-c
MOTS-c is a mitochondrial-derived peptide encoded in the mitochondrial genome. AMPK pathway activation and metabolic-regulation endpoints are the characterised readouts.
Mitochondrial-derived peptide
AMPK pathway activation
Metabolic regulation endpoints
Electron Carrier
NAD+
NAD+ is a coenzyme present in every living cell. It carries electrons between reactions, and studies have measured its role in mitochondrial metabolism, cell signalling and DNA repair.
Redox cofactor
Mitochondrial metabolism
DNA repair endpoints
Peptide and Cofactor
Combined
The vial pairs a signalling peptide with a metabolic cofactor. The two are characterised separately and no interaction data exists for the pair.
Signalling and cofactor arms
Matched handling
Interaction not characterised
Uses & Applications
What MOTS-c / NAD+ is researched for
The main areas MOTS-c / NAD+ is being studied for - and the study-reported figures behind them.
Cell Biology
Mitochondrial Function
Both compounds are studied in mitochondrial models from different angles.
Metabolic
Metabolic Regulation
MOTS-c is characterised for AMPK-pathway activation in metabolic models.
Biochemistry
Redox Studies
NAD+ is a standard cofactor in electron-transfer and redox assay work.
Methods
Parallel Protocols
One vial holds both compounds under matched handling.
Study-reported magnitudes
Representative figures from published research. Bars fill as you scroll.
MOTS-c AMPK ActivationCharacterised
NAD+ Redox ChemistryWell characterised
Mitochondrial EndpointsMeasured
Blend Interaction DataNone
Figures are representative of published research findings and shown for reference.
Molecular Structure
The MOTS-c / NAD+ molecule
An interactive 3D model rendered from the compound record - rotate and explore its structure.
Molecular model
Sequence length
blend
Physical form
Lyophilized powder blend
Documented purity
≥99% by HPLC
Compound Information
Full specification
Components
MOTS-c + NAD+
Content
110 mg per vial (10 mg MOTS-c, 100 mg NAD+)
MOTS-C
16-amino acid mitochondrial-derived peptide
NAD+
Pyridine dinucleotide coenzyme, CAS 53-84-9
Form
Lyophilized powder blend
Purity
≥99% by HPLC
Appearance
White to off-white powder
Solubility
Water-soluble
Storage
-20°C, protected from light
Classification
Research use only
FAQ
Common questions about MOTS-c / NAD+
They sit on the same subject from different sides: MOTS-c is a mitochondrial-derived signalling peptide, NAD+ is the coenzyme that carries electrons through mitochondrial metabolism. One vial holds both under matched handling.
No. NAD+ is a pyridine dinucleotide coenzyme, not a peptide. It is included here as the cofactor arm of the blend and is characterised as a small molecule rather than by amino acid sequence.
No. Each compound is characterised separately and no interaction data exists for the pair.
The separate products let you control each quantity independently and are offered in several sizes. This vial fixes the ratio at 10 mg and 100 mg.
Each lot is analysed by reverse-phase HPLC and released at ≥99%, with a Certificate of Analysis.
Store lyophilized at -20°C for long-term stability, protected from light and moisture, and avoid repeated freeze-thaw cycles.
Research Use Only.
Not for human or veterinary use. For in-vitro laboratory research only. These statements have not been evaluated by the FDA; this product is not intended to diagnose, treat, cure, or prevent any disease. Sold exclusively to qualified researchers and institutions.
