Preclinical study index · Research use only

ARA-290: preclinical and in-vitro studies

8 published studies on ARA-290, limited by rule to animal models and cell-based (in vitro) work indexed in PubMed, spanning 2018 to 2025 across 8 journals. Human trials, case reports and literature overviews are excluded. Titles appear as published; each links to its PubMed record and, where one is registered, its DOI.

  • 8studies listed
  • 8with an animal model
  • 4with in-vitro work
  • 2018 to 2025publication years
  • 8journals

Evidence table

#YearStudyJournalModelRecord
1 2025 ARA290 Attenuates Apical Periodontitis via SIRT1/NF-κB/IL-1β Pathway ModulationPMID 40680515 International dental journal Mice model and in vitro PubMed · DOI
2 2025 ARA290, an alternative of erythropoietin, inhibits activation of NLRP3 inflammasome in schwann cells after sciatic nerve injuryPMID 40216181 European journal of pharmacology Rats model PubMed · DOI
3 2024 Erythropoietin-derived peptide ARA290 mediates brain tissue protection through the β-common receptor in mice with cerebral ischemic strokePMID 38488446 CNS neuroscience & therapeutics Mice model PubMed · DOI
4 2022 Early monocyte modulation by the non-erythropoietic peptide ARA 290 decelerates AD-like pathology progressionPMID 34343617 Brain, behavior, and immunity Mice model PubMed · DOI
5 2021 The Non-Erythropoietic EPO Analogue Cibinetide Inhibits Osteoclastogenesis In Vitro and Increases Bone Mineral Density in MicePMID 35008482 International journal of molecular sciences Mice model and in vitro PubMed · DOI
6 2020 Improvement of Islet Allograft Function Using Cibinetide, an Innate Repair Receptor LigandPMID 32345869 Transplantation Mice model and in vitro PubMed · DOI
7 2019 The vasoreparative potential of endothelial colony-forming cells in the ischemic retina is enhanced by cibinetide, a non-hematopoietic erythropoietin mimeticPMID 30876881 Experimental eye research Mice model and in vitro PubMed · DOI
8 2018 Activation of the EPOR-β common receptor complex by cibinetide ameliorates impaired wound healing in mice with genetic diabetesPMID 29223734 Biochimica et biophysica acta. Molecular basis of disease Mice model PubMed · DOI

Studies by model

  • Mice · 7 studies
  • In vitro · 4 studies
  • Rats · 1 study

What this index does not include

Human research of any kind: publications typed by PubMed as human studies or case reports, and papers whose titles or abstracts describe human subjects, are removed by rule. Literature overviews, meta-analyses, editorials and letters are removed because they summarise rather than report. Papers whose titles contain usage or outcome language that would not pass this site's research-use-only copy rules are dropped rather than reworded, since a published title is a fact that cannot be edited.

Nothing on this page is a statement about effects in humans, a recommendation, or a description of the material supplied. ARA-290 is supplied for laboratory research only.

How this index is built

PubMed is searched on the names the literature uses for ARA-290 (ARA 290, ARA-290, ARA290, cibinetide), restricted to records indexed to an animal or cell model, in English, with an abstract. Clinical publication types, human-subject language and overview-type publications are excluded. The compound must be named in the title. Candidates are ranked by title match, indexing quality and year; the shortlist is read by a person before it is published, and a small blocklist holds records rejected on that read. The list was resolved on 2026-10-12 and is re-run deliberately, never on a timer.

Questions

Are there human studies of ARA-290 in this index?

No, by design. This index lists animal and cell-based research only. Publications typed as human studies, case reports or literature overviews, and papers whose titles or abstracts describe human subjects, are excluded by rule before anything is listed. Eon Peptides supplies ARA-290 for laboratory research and makes no statement about use in humans.

Which research models appear most often for ARA-290?

Across the 8 studies listed: Mice (7), In vitro (4), Rats (1). A model label is taken from PubMed's indexing of each paper, or from its title and abstract when the record is too new to be indexed. It describes the study, not the material.

How are the studies selected?

A PubMed search on the published names of the compound (ARA 290, ARA-290, ARA290, cibinetide) is filtered to records indexed to an animal or cell model, with clinical publication types, human-subject language and overview-type publications removed. The compound must be named in the title. Remaining records are ranked by title match, indexing quality and year, and the top 8 are listed after a manual read. The list was resolved against PubMed on 2026-10-12.

Does a listing here say anything about the ARA-290 Eon Peptides sells?

No. A listing records that a study was published and what it examined. It says nothing about the properties, quality or intended use of any material. What Eon Peptides does document about its own ARA-290 is on the certificate pages: lot-level identity and purity results from independent laboratories.

Related pages

For research use only. Not for human or veterinary use. Preclinical and in-vitro studies only: animal models and cell-based work indexed in PubMed. Human trials, case reports and literature overviews are excluded by rule.