High-performance liquid chromatography
Pushes the dissolved sample through a column so its components separate and elute at different times. The area under each peak quantifies how much of each is present — giving the purity percentage.
DOCUMENTATION, DECODED
What a Certificate of Analysis actually tells you
A Certificate of Analysis — a COA — is the lab report that accompanies a specific batch of material. It is the difference between a supplier claiming quality and proving it. Here is what every line on ours means, and how to read it with a skeptical eye.
ANATOMY OF A CERTIFICATE
Read it line by line
1
Compound & strength
The peptide identity and the labeled quantity per vial. This is what the batch is supposed to be — every test below exists to confirm it actually is.
2
Lot / batch number
A unique code for this single production run. It ties the certificate to the exact vials it was made with — enter it on our Verify a Batch tool to pull this report back up.
3
Purity by HPLC
High-Performance Liquid Chromatography separates the sample into its components. Purity is the percentage of the total that is your target peptide — the single most important number on the page. We hold to 99%+.
4
Identity by mass spec
Liquid chromatography–mass spectrometry (LC–MS) measures the molecular weight and confirms the sample is the peptide named — not something with a similar retention time. "Confirmed" means the observed mass matches the theoretical mass.
5
Net peptide content
The actual mass of peptide recovered, which can differ from the gross fill weight because lyophilized powder also contains residual salts and water. It tells you how much active material you are really working with.
6
Appearance & test date
A visual description of the material and the date the laboratory ran the analysis. A recent date on the batch you hold is what makes the document meaningful rather than decorative.
Illustrative values shown for teaching purposes. Real certificates for released lots live in the COA library.
GLOSSARY
The terms, in plain language
Mass spectrometry
Ionizes the molecules and measures their mass-to-charge ratio. Matching the measured mass to the peptide's theoretical mass confirms identity — proving the compound is what the label says.
Net peptide content
The true mass of peptide after accounting for counter-ions, residual solvent and moisture bound up in the lyophilized cake. Often reported gravimetrically.
Endotoxin (LAL)
A test for bacterial lipopolysaccharide contamination, reported in endotoxin units per milligram. Lower is cleaner; a low result indicates careful handling during synthesis and fill.
Independent testing
Analysis performed by a laboratory with no stake in the result — not the seller's in-house bench. It removes the conflict of interest that makes a self-reported number worth little.
Lot traceability
Every certificate is bound to a lot number, so any vial can be matched back to the exact report for the batch it came from — not a generic sample of a different run.
WHY IT MATTERS
A number you can't check is just marketing
Anyone can print "99% pure" on a label. What separates documentation from a claim is whether you can trace that number to an independent report, tied to the specific batch in your hand, dated recently, and readable in full. That is the entire point of publishing every certificate up front — so the evidence sits in front of you before you ever place an order.
See the real certificates
Browse every documented batch, or look up the exact lot printed on your vial.